Indulge in the ultimate comfort food experience with the Best Meatloaf in a Tomato Sauce recipe. This hearty dish combines the savory goodness of ground beef and turkey with a flavorful tomato sauce, creating a meal that’s both satisfying and delicious. Whether you’re cooking for a family dinner or entertaining guests, this recipe is sure to impress.

Why Make Best Meatloaf in a Tomato Sauce

  • A classic comfort food dish with a twist, this meatloaf is elevated by the addition of a tangy tomato sauce.
  • Perfect for meat lovers and those craving a hearty, home-cooked meal.
  • Simple ingredients and easy preparation make this recipe ideal for busy weeknights or lazy weekends.


  • Medium yellow onion
  • Garlic
  • Parsley leaves
  • Ground beef (90% lean)
  • Ground turkey
  • Panko breadcrumbs
  • Parmesan cheese
  • Milk
  • Egg
  • Dried Italian seasoning
  • Crushed San Marzano tomatoes
  • Angel hair pasta
  • Extra virgin olive oil
  • Coarse salt
  • Freshly ground pepper

How to Make Best Meatloaf in a Tomato Sauce

  1. Preheat the oven: Preheat your oven to 350°F (175°C).
  2. Prepare the onion mixture: In a food processor, combine the onion, garlic, and parsley. Pulse until finely chopped.
  3. Mix the meatloaf ingredients: In a large bowl, mix together the ground beef, ground turkey, onion mixture, Panko breadcrumbs, Parmesan cheese, milk, egg, Italian seasoning, salt, and pepper until well combined.
  4. Shape the meatloaf: Transfer the mixture to a flat surface and shape it into a loaf. Place the loaf in the center of a casserole dish.
  5. Prepare the tomato sauce: Pour the crushed tomatoes around the meatloaf in the casserole dish. Brush some of the tomatoes over the top of the loaf and sprinkle with salt.
  6. Bake: Bake the meatloaf in the preheated oven for 1 hour and 15 minutes, or until cooked through.
  7. Cook the pasta: While the meatloaf is baking, cook the angel hair pasta according to package instructions until al dente. Drain and toss with olive oil and a pinch of salt.
  8. Serve: Slice the meatloaf and serve it with the cooked pasta, topped with additional tomato sauce. Garnish with parsley and Parmesan cheese.

Serving Suggestions

  • Serve the meatloaf alongside roasted vegetables or a fresh green salad for a complete meal.
  • Pair it with garlic bread or dinner rolls for a comforting dinner option.

Storage Info

  • Store any leftovers in an airtight container in the refrigerator for up to 3 days.
  • Reheat individual portions in the microwave or oven until warmed through.

Techniques or Tips

  • Let the meatloaf sit out at room temperature for about 30 minutes before mixing to prevent your hands from getting too cold.
  • Use lean ground beef and turkey for a healthier version of this classic dish.
  • Don’t overmix the meatloaf mixture to keep it tender and moist.


  • Experiment with different herbs and spices in the meatloaf mixture, such as thyme, rosemary, or chili flakes, to customize the flavor to your liking.

FAQs about Best Meatloaf in a Tomato Sauce

Q: Can I use different types of meat in this recipe? A: Yes, feel free to experiment with different combinations of ground meat, such as beef, pork, or chicken, according to your preference.

Q: Can I make this recipe ahead of time? A: Yes, you can prepare the meatloaf mixture and shape it in advance, then cover and refrigerate until ready to bake. You can also freeze the unbaked meatloaf for later use.

Q: Can I use homemade tomato sauce instead of canned? A: Absolutely! Homemade tomato sauce will add a fresh and vibrant flavor to the meatloaf. Simply substitute an equal amount of homemade sauce for the canned tomatoes in the recipe.

For ingredients and comprehensive cooking instructions, please proceed to the next page or click the open button (>)—and be sure to share with your Facebook friends!

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Written by Belkys mieles

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