New on the blog! Johnny Marzetti Casserole features ground beef, sausage, mushrooms, onions, and bell peppers, in tomato sauce, all smothered with cheddar and mozzarella cheese.


There’s something incredibly comforting about a casserole, especially when it’s packed with flavorful ingredients like ground beef, sausage, mushrooms, onions, and colorful bell peppers. This dish isn’t just a feast for the eyes; it’s a heartwarming family favorite that marries protein and veggies in a luscious tomato sauce, all topped off with melted cheddar and mozzarella cheese. Whether it’s a chilly weeknight or you’re hosting friends on a weekend, this recipe is bound to be a hit on any table.
Reasons to try it
You might be wondering why this casserole stands out among the many comfort food options out there. First off, it’s a time-saver that offers a burst of flavor without demanding hours in the kitchen. With ingredients that are often already found in your fridge or pantry, it’s also budget-friendly, making it an ideal choice for a family meal or casual gathering. You can whip this up in less than an hour—perfect for busy weeknights when you still want to serve something satisfying and delicious.
"I never thought a casserole could taste this good! My kids absolutely devoured it and I’ve been asked to make it again next week!" – Home Cook Enthusiast
The cooking process explained
Now that you’re convinced to try this delightful casserole, let’s break down how the magic happens. Start by preheating your oven and gathering your ingredients. This dish comes together seamlessly, allowing you to chop, sauté, and mix everything in one pot before transferring it to the oven. The whole cooking process is quick and straightforward, ensuring you won’t spend your evening slaving away in the kitchen.
What you’ll need


To create your own masterpiece, here’s what you’ll need:
- Ground beef
- Italian sausage
- Mushrooms
- Onions
- Bell peppers (red and green for visual appeal)
- Tomato sauce
- Cheddar cheese
- Mozzarella cheese
- Optional: spices like garlic powder or Italian seasoning for extra flavor
Feel free to swap in turkey or chicken sausage for a lighter dish, or even add some spinach for a nutritional boost!
Step-by-step instructions
- Preheat your oven to 375°F (190°C).
- Cook the meat: In a large skillet, cook the ground beef and sausage over medium heat until browned. Drain excess fat.
- Sauté the vegetables: Add chopped onions, bell peppers, and mushrooms to the skillet. Cook until they’re soft, about 5 minutes.
- Add the sauce: Stir in the tomato sauce and let it simmer for a few minutes, combining all flavors.
- Layer it up: In a prepared baking dish, pour the meat and veggie mixture. Top with a generous layer of cheddar and mozzarella cheese.
- Bake: Place the dish in the preheated oven and bake for about 25-30 minutes, or until the cheese is bubbly and golden.
- Cool and serve: Let it sit for a few minutes before serving, allowing the flavors to meld beautifully.
Best ways to enjoy it
When it comes to serving this casserole, the options are endless. A sprinkle of fresh parsley on top adds a delightful touch, turning a humble dish into something special. Pair it with a crisp side salad for contrast or garlic bread for that extra indulgence. And don’t forget a glass of red wine—it’s the perfect companion to enhance the meal.
Keeping leftovers fresh
Storing this casserole is straightforward! Allow it to cool completely before transferring it to an airtight container. It will keep well in the refrigerator for up to 3-4 days. Want to save some for later? This casserole freezes beautifully; just make sure to wrap it tightly. It can be stored in the freezer for up to 3 months. When you’re ready to enjoy it again, thaw it overnight in the fridge before reheating in the oven until hot.
Pro chef tips
- Don’t rush the browning: Letting the meat brown completely enhances the flavor profile.
- Cheese alternatives: Try adding provolone or fontina cheese for different flavor dimensions.
- Add some heat: If you enjoy spicy food, sprinkle in some red pepper flakes with the veg for extra zest.
- Prep ahead: You can assemble the casserole a day in advance. Just pop it in the oven when you’re ready to bake!
Creative twists
Casseroles are custom-made for experimentation! Here are some ideas:
- Swap out the meats for your favorite proteins like ground turkey or even shredded chicken.
- Go vegetarian by using lentils or chickpeas as a protein substitute.
- Experiment with different cheeses for a unique flavor finish, such as goat cheese or even a blend of gourmet cheeses.
Common questions
What is the prep time for this casserole?
You can expect around 15 minutes of prep time, followed by 30 minutes of cooking.
Can I substitute the ground beef?
Absolutely! Ground turkey or chicken work well and are leaner options.
How can I make this dish gluten-free?
Make sure that the sausage and tomato sauce you choose are gluten-free. All other ingredients are naturally gluten-free!
With this guide in hand, you’re well on your way to creating an unforgettable Johnny Marzetti Casserole that will leave everyone craving seconds. Enjoy the cooking adventure!






